The service and health group signed a three-year agreement for non-emergency flight and road transport at Horsham Aerodrome yesterday.

Health care group chief executive Chris Scott said the agreement would ease strain on the region's hospitals, as well as Ambulance Victoria.

"It frees up a lot of our assets so we can have patients flow through the organisation a lot quicker and we can get patients back in their communities," he said.

"It also frees up Ambulance Victoria to do what they do best.

"It gives people comfort because they know there are people who can look after them with these road and air assets."

Royal Flying Doctor Service Victoria chief executive Scott Chapman said it took about two years to reach an agreement.

He said the flying doctors no longer just serviced outback areas.

"We have targeted the big regional areas," he said.

"A lot of our work is done in rural and regional areas, as well as in cities.

"We are looking at where we can best provide the service; we have found the more we talked, the more we realised there was a need here."

Horsham has more people who donate money to the Royal Flying Doctor Service per capita than any other Victorian town or city.

Horsham man Arty Hopper has raised money for about 35 years.

"We just want to earn a few quid for the Royal Flying Doctor Service - that is all I want and every dollar counts," he said.

"I used to work on an outback station so I got to know how important the service was it would take two and a half hours just to get to the mailbox.

"This agreement will be very good for Horsham."