Grampians Tourism remains positive for the region despite the announcement that the border between Victoria and New South Wales would be closed as of Tuesday night.
The announcement coincides with South Australia abandoning its decision to open its border with Victoria to travellers on July 20 because of a spike in coronavirus cases across the state.
Research undertaken by the tourism body showed if state and international borders remained closed there was a surplus in the Victorian visitor spending economy.
The key is for Victorians to be able to travel internally, without further statewide lockdowns.
"We spend more money overseas and interstate than we do in intrastate travel," chief executive Marc Sleeman said.
"If the borders remain closed and we were able to activate visitation there is a net positive $10m that could flow out to regional economies."
"Fifty per cent of visitation at the moment is from regional Victoria," he said.
"Melbourne only ever represented 30 per cent of visitation to our region anyway. The regional visitation is one of our source markets for visitation to the region and contributes more visitor spend than other markets."
Mr Sleeman said some people held concerns about the impact of people travelling from postcodes which were in lockdown.
"The top 10 sources of visitors from local government areas from greater Melbourne are not those areas," he said.
"If we follow the chief medical officer's advice on opening businesses in the COVID-19 climate we will ensure we maintain safety for our staff and visitors. This will enable us to rebound strongly. "
Lake Fyans Holiday Park has felt the impacts due to the closure of the border between South Australia and Victoria.
Holidaymakers who had planned to travel interstate to the Grampians region for the second week of the South Australian school holidays have cancelled their plans.
"We would have had people from interstate start to arrive this week and into next week for the cross over of school holidays," park manager Janine Palensky said.
"I think a lot of people are of the understanding regional areas have had very minimal cases and no active ones for a long time.
"I think they are worried about other visitors within the park."