Three people have been taken to the Wimmera Base Hospital in a stable condition after a collision on the intersection of Blue Ribbon and Wallup Hall roads.
Emergency services attended the scene at 8.50am, with Police, two CFA trucks, two ambulances and a SES vehicle in attendance.
Warracknabeal Police Station first constable Leigh Edwards said the driver of a Ford Falcon travelling east across Wallup Hall Road failed to give way to a four-wheel drive travelling south on Blue Ribbon Road.
The driver of the four-wheeled drive sustained superficial cuts to their head.
Both occupants of the four-wheeled drive and the driver of the Falcon were taken to the hospital.
First constable Edwards urged motorist to exercise more caution on regional roads.
"Luckily people have come out of this alive," he said.
"I advise drivers to slow down at intersections and give way to other motorists."
Police temporarily stopped traffic through the intersection which has since opened.
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