Across the border, South Australian government MP Nick McBride, whose electorate covers Bordertown, Naracoorte and Lucindale, said the restrictions would possibly not last long.

"I have had discussions with South Australian police, and they are hopeful that these new restrictions will be in place for the relatively short timeframe of 3 - 4 weeks," he said.

"I understand these new restrictions will be one of the first to be relaxed when the number of COVID cases in regional Victoria reduce.

"I have communicated the complicated reality of these changes to both SA Health and Police. I am - and will continue to advocate for our Cross-Border Community members, who, while divided by the border, I know - call South Australia home.

"I have been talking to my cross border parliamentary colleagues to look at ways we can support this community at this difficult time."

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Victorian Premier Daniel Andrews has suggested the government could look at helping far western Victorian residents set to be deeply inconvenienced the South Australian border closure.

On Wednesday, the South Australian Police Commissioner Grant Stevens said Cross Border Community Members that travel to or from Victoria are no longer permitted to enter South Australia as of August 21, with few exemptions.

It means residents of towns such as Kaniva, Serviceton, Edenhope and Apsley will no longer be able to shop, study school or visit family in South Australia, but only go to carry out essential services such as agricultural work.

At a regional press conference via Zoom on Friday, the premier expressed sympathy for people that will be affected by this move and said Victoria might need to make exemptions for these residents in response.

"It is a concern whenever the South Australian government or we fundamentally alter normal patterns of movement," he said.

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"We don't want people to go without, to have to deal with those sorts of changes.

"The stage three (lockdown) rules are there to protect every Victorian, but I think the circumstances over in the far west are in some respects unique.

"I am certainly happy to commit... it might mean we need to try and have some different arrangements around freedom of movement in order to get the things that people need.

"We need to have a sense of: Can we bring services into those communities, or can we make arrangements to try and maximise the safety and decrease the risk of that movement further inland?"

Mr Andrews also thanked all regional Victorians for taking stage three restrictions seriously.

The Mail-Times has contacted the office of Agriculture and Regional Development Minister Jaclyn Symes for comment on the cross-border discussions taking place between Victoria and South Australia.

More to come.